From ISOGG Wiki
|Industry||Genealogy, DTC genetic testing|
|Founder(s)||Professor Bryan Sykes|
|Headquarters||Kidlington, Oxfordshire, England|
|Products||mtDNA Tests, Y-STR tests|
Oxford Ancestors is a commercial genetic genealogy company launched in May 2000 by Professor Bryan Sykes, a Professor of Human Genetics at the University of Oxford. Oxford Ancestors was set up to meet the anticipated demand for mitochondrial DNA (mtDNA) tests from members of the public in response to the publication of Sykes' book The Seven Daughters of Eve (published spring 2001) which claimed to show that almost everyone in Europe was descended on the maternal line from one of seven female ancestors. The "daughters" or clans correspond to the most common mitochondrial DNA haplogroups in Europe. For a list of the clan mother names used by Oxford Ancestors for the mtDNA haplogroups see the ISOGG Wiki list Oxford Ancestors haplogroup nicknames.
Sykes was one of the first researchers to establish a link between the Y chromosome and surnames. His paper "Surnames and the Y chromosome" suggested that the surname Sykes had a single surname founder, even though written sources had predicted multiple origins. A Y chromosome test was also offered to the public on the company's launch. Oxford Ancestors similarly assign clan names to the Y-DNA haplogroups.
The company currently offers the following products:
- The MatriLine test sequences a client's mitochondrial DNA and identifies which of the "seven daughters" (haplogroups) is the client's own ancestor and describes her imagined life. The Matriline test is a low-resolution HVR1 (hypervariable region 1) mitochondrial DNA test suitable for deep ancestry purposes only.
- Y-Clan is a basic low-resolution Y-chromosome DNA test. The company will deduce your "paternal clan and your ancient ancestral father". The Y-Clan test originally looked at just 10 Y-STR markers. The number of markers has since been increased and results are now given for 15 markers. The Y-Clan + 50 analysis was introduced in the summer of 2013. This test looks at an additional 50 Y-STR markers bringing the total number of markers tested to 65. Note that for genetic genealogy purposes a 15-marker test does not provide sufficient resolution for surname matches.
- Tribes of Britain service. If your paternal roots are in Britain or Ireland this Y-clan analysis test purports to tell you whether you are descended from a Celt, Saxon or Viking. The service is based on research from Professor Sykes' laboratory on the genetic history of Britain and Ireland, which was published in the book Blood of the Isles (published in the US and Canada as Saxons, Vikings and Celts: The Genetic Roots of Britain and Ireland). Sample Tribes of Britain reports can be seen here and here. Note, however, that these reports are for entertainment value only and do not have any scientific basis.
- Make mine a double helix by Max Davidson, The Telegraph, 12 April 2008
- Curiosity drives the gene genie to a £1m turnover Report by Martin Baker, Daily Telegraph 14 February 2008.
- Ancestors reunited: 10 numbers that can trace your family tree by Chris Gray, The Independent, August 2002.
- Profile of David Ashworth of Oxford Ancestors
- Genghis Khan or not? That is the question Tom Robinson, 16 June 2006 (Internet Archive version). See also the story in the New York Times Falling from Genghis's family tree by Nicholas Wade, 21 June 2006
- My DNA lineages - from Oxford Ancestors Nigel Seal. Wading through Treacle blog, 28 November 2008.
- Campbell KD. Geographic patterns of haplogroup R1b in the British Isles. Journal of Genetic Genealogy 2007; 3: 1-13. An independent analysis of the data from the Oxford Genetic Atlas Project.
- Bryan Sykes and Catherine Irven. Surnames and the Y Chromosome. American Journal of Human Genetics, April 2000, Vol 66, issue 4, pp1417–1419.
- Y Clan +50 Oxford Ancestors website, accessed 6 May 2013.
- Shriver MD, Kittles RA. Genetic ancestry and the search for personalized genetic histories. Nature Reviews Genetics 2004: 5: 611-618.
- Oxford Ancestors official site
- Oxford Genetic Atlas Project results The results are available as PDF files which are downloadable from the archived version of the website in the Internet Archive
- 13-13-23 distribution Leo Little's compilation of the distribution of DYS390=23, DYS392=13, and DYS393=13 in YHRD and in Blood of the Isles (by B.C. Sykes, Bantam Press, 2006)
- mtDNA clan names and descriptions used by Oxford Ancestors
- Y-DNA clan names and descriptions used by Oxford Ancestors
- Wikipedia article on Bryan Sykes