DNA databases
From ISOGG Wiki
There are a number of public DNA databases that can be used by the genetic genealogist. Some provide a facility for people to enter their DNA results and search for close or exact matches. Other databases are publicly searchable but it is not possible to input your own results.
Contents
List of DNA databases
MTDNA databases
- AmtDB - a database of ancient human mitochondrial genomes Paper here
- Empop A worldwide forensic database of mtDNA control region haplotypes
- GenBank, a public database of DNA sequences. Genetic genealogists who have taken a full mitochondrial sequence (FMS) mitochondrial DNA test can upload their FMS results for comparison with other sequences.
- Geni.com. Geni.com introduced DNA matching in July 2016. Customers can integrate their Y-DNA, mtDNA and autosomal DNA results from Family Tree DNA with their Geni tree.
- WikiTree: lists DNA testers, their DNA test information, GEDmatch and mitoYDNA ID's, with links from the ancestors profile to matches and comparisons on these third-party sites, on a tester's ancestor's profile. It also has categories like this one, H1b1-T16362C FS mtDNA Haplogroup, placed on the EKA (earliest known ancestor) of the Full Sequence mitochondrial DNA tester.
- Helix mitochondrial DNA database A downloadable database of aggregated and de-identified mitochondrial DNA variants observed in individuals sequenced at Helix.
- mitoYDNA.org - A Public mtDNA website for uploading Y-DNA and mitochondrial DNA results to create a YDNA and mitochondrial DNA database. The site is volunteer-driven and is accessible to all.
- Human mitochondrial genome database For a description see: Ingman M, Gyllensten U. mtDB: Human Mitochondrial Genome Database, a resource for population genetics and medical sciences. Nucleic Acids Research 34, D749-D751 (2006).
- MitoVariome A freely available database of 5344 mtDNA sequences from around the world.
- MSeqDR Consortium The Mitochondrial Disease Sequence Data Resource (MSeqDR) Consortium
- mtDNA test results log A genealogical mtDNA database maintained by Charles Kerchner
Y-DNA databases
- Geni.com. Geni.com introduced DNA matching in July 2016. Customers can integrate their Y-DNA, mtDNA and autosomal DNA results from Family Tree DNA with their Geni tree. Uploads are also accepted of autosomal DNA data from 23andMe and AncestryDNA.
- mitoYDNA.org - A Public mtDNA website for uploading Y-DNA and mitochondrial DNA to create a YDNA and mitochondrial DNA database. The site is volunteer drive and will be accessible to all.
- WikiTree lists DNA testers, their DNA test information, GEDmatch and mitoYDNA ID's, with links from the ancestors profile to matches and comparisons on these third-party sites, on a testers ancesters profile.
- YDHS database For a description see Human chromosome Y and haplogroups: introducing YDHS database (Tiirikka1 T, Moilanen JS, Clinical and Translational Medicine 2015; 4: 20).
- Yfiler Y-STR database
- YHRD, a freely accessible YHRD (Y Chromosome Haplotype Reference Database which is designed to store Y-STR haplotypes from global populations for both forensic genetics and genetic genealogy.
- US Y-STR database A database for estimating Y-STR haplotype population frequencies.
Autosomal SNP databases
- GEDmatch A cross-testing company comparison site owned by the forensic science company Verogen. The site allows uploads from over 20 different companies.
- Geni.com. Geni.com introduced DNA matching in July 2016. Customers can integrate their Y-DNA, mtDNA and autosomal DNA results from Family Tree DNA with their Geni tree. Uploads are also accepted of autosomal DNA data from 23andMe and AncestryDNA.
- Open Humans A project initiated by the Personal Genome Project. Users can share their data, including genome, microbiome, and viral surveillance research data, with other users and researchers for the advancement of science.
- WikiTree lists DNA testers, their DNA test information, GEDmatch ID's, with links from the ancestors profile to matches and comparisons at GEDmatch, on a testers ancesters profile.
- Open SNP A public database of genotyping files uploaded by customers of direct-to-consumer testing companies. The database includes files from 23andMe, DeCODE genetics and FTDNA's Family Finder test
Note that some of the major testing companies also accept uploads. See the autosomal DNA testing comparison chart.
Autosomal STR databases
Ancient DNA databases
Former DNA databases
- DNA.Land A website run by a team of academics. Uploads were accepted from five companies. The site offered a biogeographical analysis, imputation, relative-matching feature, importing data from Geni.com, and a relatives of relatives report.
- mtDNACommunity A public database of full mitochondrial sequence DNA results. This database was closed on 5th January 2018. An archived version of the website from December 2017 can be seen in the Wayback Machine.
- Geneanet A French genealogy website, bought out by Ancestry in 2021, introduced the ability to upload DNA profiles in 2020. Uploads were no longer accepted from 20 November 2023 and the site will be deleted on 20 December 2023.
- Y-search, a public Y-STR database sponsored by Family Tree DNA (This closed down at the end of May 2018)
- Mitosearch was a public mtDNA database sponsored by Family Tree DNA. (This closed down at the end of May 2018.)
- Semargl.me A website with a variety of searching mechanisms for querying large Y-STR databases such as Ysearch and Family Tree DNA
- SMGF Y-DNA database The Y-DNA database of the Sorenson Molecular Genealogy Foundation (Wayback Machine version from 14 April 2015).
- SMGF mtdna database The mtDNA database of the Sorenson Molecular Genealogy Foundation (Wayback Machine version from 14 April 2015).
- The SMGF website and databases were taken down on 14th May 2015 and there are no plans to reinstate them.[1]
- Ybase (Wayback Machine version from November 2010), a public Y-STR database sponsored by DNA Heritage. The domain name was purchased by Family Tree DNA when it acquired DNA Heritage in 2011. The database has been offline from 2011 onwards and it is not known if FTDNA have any plans to resurrect it.
Scientific papers
- Kaiser J (2015). Who has your DNA - or who wants it? Science 349 (6255): 1475.
- Alessandra Congiu, Paolo Anagnostou, Nicola Milia, Marco Capocasa, Francesco Montinaro and Giovanni Destro Bisol (2012). Online databases for mtDNA and Y chromosome polymorphisms in human populations. Journal of Anthropological Sciences 90: 1-15.
References
- ↑ Estes R. RIP Sorenson - a crushing loss. DNAeXplained blog, 14 May 2015.