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Neanderthal DNA Neanderthal
skulls were first discovered in Engis, Belgium, in 1829, but
derive their name from the Neander Valley in Germany, the site
of a later find in 1856. For many years, the debate has
raged as to whether Neanderthals are a predecessor to modern
humans. Mitochondrial
DNA extracted from ancient Neanderthal remains have been typed and found to differ
significantly from human mitochondrial DNA. (Source)
While the results do not indicate a
common ancestry, a team of scientists in Germany have recovered and sequenced
Y-chromosome DNA from a 49,000 year-old Neanderthal.
The team estimates that Homo sapiens
sapiens and
Homo neanderthalensis may have
shared a common ancestor in the Homo
genus several hundred thousand years ago. (Source)
Update:
16 May 2006 The
following seven Neanderthal mitochondrial DNA sequences are found in GENBANK
under 'homo
sapiens neanderthalensis' and have been converted by Ian Logan:
| HVR1 |
Haplotype |
| AF254446 |
T16086C G16129A
A16139T C16148T G16156A C16169T A16182. A16183. T16189C
16193.C
16193.C T16209C C16223T A16230G C16234T G16244A C16256A
C16262T 16263.A C16278T
A16299G T16311C C16320T C16344T T16362C |
| HVR1 |
Haplotype |
| AF011222 |
A16037G A16078G
T16093C C16107T C16108T C16111T C16112T G16129A A16139T
C16148T
T16154C C16169T A16183. T16189C 16193.C T16209C C16223T
A16230G C16234T G16244A
C16256A A16258G C16262T 16263.A C16278T A16299G T16311C
C16320T T16362C C16400T |
| HVR1 |
Haplotype |
AF282971
|
A16037G A16078G
G16129A A16139T C16148T T16154C C16169T A16182. A16183.
T16189C
16193.C 16193.C T16209C C16223T A16230G C16234T G16244A
C16256A A16258G C16262T
16263.A C16278T A16299G T16311C C16320T T16362C |
| HVR1 |
Haplotype |
AY149291
|
A16037G A16078G
G16129A A16139T C16148T T16154C C16169T A16182. A16183.
T16189C
16193.C 16193.C T16209C C16223T A16230G C16234T G16244A
C16256A C16262T 16263.A
C16278T A16299G T16311C C16320T T16362C |
| HVR1 |
Haplotype |
| DQ464008
(Belgium) |
C16223T A16230G
C16234T T16243C G16244A C16256A C16262T 16263.A C16266T
C16278T C16291T A16299G T16311C C16320T
|
| HVR2 |
Haplotype |
AF282972
|
A73G
T146C C150T T152C
A189G A200G A243G
T245C G247A C262T
A263G 304.T C338T |
| HVR2 |
Haplotype |
| AF142095 |
A73G
T146C C150T T152C
A189G A243G T245C
G247A C262T A263G
307.T 307.T 307.T
T391C
|
NOTE: The purpose of the "Neanderthal
DNA" page is to provide a compilation of DNA results of ancient
homo neanderthalensis
for comparison and
educational purposes only. The HVR1 region spans 16024
-16383 and HVR2 is 57-372.
More articles:
Neanderthal
Man
|
