23andMe versus deCODEme

From ISOGG Wiki

This page on 23andMe versus deCODEme seeks to compare the autosomal DNA test offerings from 23andMe and deCODE genetics. Note that the 23andME data refer to the version 2 chip. The information has not yet been updated to reflect the changeover to the version 3 chip which was offered from November 2010 onwards.

Contents 1 Overview 1.1 23andMe 1.2 deCODEme 1.3 Autosomal SNPs in common 2 See also 3 External links

Overview

23andMe

• Uses customized 550K SNP chip from Illumina
• Tests 578,320 autosomal DNA SNPs
• Tests 1,800 Y chromosome SNPs
• Tests 14,000 X chromosome SNPs
• Tests 3,000 mtDNA SNPs
• Ancestry Painting attempts to predict from which of three regions of the world your ancestors came (Europe, Africa, Asia)
• Ancestry Finder attempts to predict from which countries of the world your ancestors came
• Native American Ancestry Finder attempts to predict whether a person has NA Ancestry in the last five generations
• Global Similarity illustrates to which countries or ethnic groups one is most closely related
• Family Inheritance: Advanced Lab graphically illustrates the matching DNA segments between customers
• Gives information based on scientific studies about medical conditions to which one might be predisposed
• Gives information in regard to Mendelian disease carrier status
• Gives information based on scientific studies about individual traits
• Allows comparisons to other people using Relative Finder
• Customers can download their raw data but only if they have ordered the Complete Edition
• Does not allow upload of raw data from other companies

deCODEme

• Uses Human1M SNP chip from Illumina
• Tests 1,072,820 autosomal DNA SNPs
• Tests about 858 Y chromosome SNPs
• Tests 40,097 X chromosome SNPs
• Tests 173 mtDNA SNPs
• Tells which regions of the world your ancestors came from
• Gives information based on scientific studies about medical conditions to which one might be predisposed
• Gives information in regard to Mendelian disease carrier status
• Gives information based on scientific studies about individual traits
• Allows comparisons to other people
• Customers can download their raw data

Autosomal SNPs in common

• SNPs in common: 554,618
• SNPs unique to 23andMe: 23,702
• SNPs unique to deCODEme: 458,731
• Conclusion: If you have already done the deCODEme test, then doing the 23andMe test won’t add much new information

See also

• Family Finder versus deCODEme
• Family Finder versus Relative Finder

External links

• Ann Turner on Personal Genomics Companies 23andMe vs deCODEme Note from Ann Turner: the material is more than two years old now and some items are out of date.

• You 2.0: Are genetic tests really useful. A four-part series by David Ewing Duncan providing a comparison of test results from 23andMe, deCODEme and Navigenics:
• Part 1: Comparison Shopping for Your Future
• Part 2: I'm Doomed. Or Not
• Part 3: Recreational DNA and Genetic Voyeurism
• Part 4: Closing the Genetic Gap